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NORCO® 10/325 mg: (hydrocodone bitartrate and paracetamol) tablets USP 10/325 mg
NORCO® ( Hydrocodone Bitartrate and Acetaminophen ) is supplied in tablet form for oral administration.
Hydrocodone bitartrate is an opioid analgesic and antitussive and comes as fine, white crystals or as a crystalline powder. It is influenced by light. The chemical name is 4,5α-epoxy-3-methoxy-17-methylmorphinan-6-one-tartrate (1: 1) hydrate (2: 5).
Hydrocodone Bitartrate – Structural Formula Illustration
Acetaminophen, 4´-Hydroxyacetanilid, a slightly bitter, white, odorless, crystalline powder, is an opiate-free, salicylate-free analgesic and antipyretic.
Acetaminophen – Structural
Formula Illustration Each NORCO® 10/325 tablet contains:
Hydrocodone bitartrate …… 10 mg
Acetaminophen ………….. 325 mg
In addition, each tablet contains the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, crospovidone, microcrystalline cellulose, povidone, pregelatinized starch, stearic acid and sugar globules made from starch from corn, sucrose and FD&C Yellow # 6.
NORCO is indicated for the relief of moderate to moderately severe pain.
DOSAGE AND APPLICATION
The dosage should be adjusted according to the severity of the pain and the patient’s response. However, it should be noted that with continued use, tolerance to hydrocodone may develop and the occurrence of side effects is dose-dependent.
The usual dose for adults is one or two tablets every four to six hours, as needed. The total daily dose should not exceed 8 tablets.
NORCO® 10/325 tablets (hydrocodone bitartrate and acetaminophen tablets, USP 10 mg / 325 mg) contain hydrocodone bitartrate 10 mg and acetaminophen 325 mg. They are supplied as white with orange spots, capsule-shaped, halved tablets debossed with WATSON on one side and 913 on the other.
Store at a controlled room temperature of 15 ° -30 ° C (59 ° -86 ° F).
Dispense in a tight, light-resistant container with a child-resistant closure.